Sedative laced toothpaste

ABSTRACT

A toothpaste product that is laced with, or infused with, a sedative such as the active ingredients in cannabis. The act of brushing one&#39;s teeth using the present invention transfers the sedative into the bloodstream through contact with the gums, leading to a more restful sleep.

CROSS-REFERENCES TO RELATED APPLICATIONS

This is a continuation based U.S. Ser. No. 16/728,256, filed on Dec. 27,2019, which claims priority from U.S. Ser. No. 62/787,708, filed Jan. 2,2019, the contents of which are incorporated herein by reference intheir entirety.

BACKGROUND

Toothpastes and other oral care products are used to combat tooth decay,gum disease, and overall oral health. Brushing one's teeth beforebedtime is a healthy routine recommended for good dental health andshared by many millions of people around the world. It is also knownthat millions of people suffer from insomnia, restlessness, anxiety, andsleep disorders relating to the inability to relax before a scheduledbedtime. The present invention aims to address the latter problems byutilizing an improved therapeutic toothpaste to be used in the former.

U.S. Pat. No. 9,763,991 entitled Composition For The Treatment OfNeurobehavioral Disorders, the contents of which are fully incorporatedherein by reference, teaches the benefits of cannabinol and otherderivatives of cannabis to treat insomnia, among other disorders. The'991 Patent extolls the benefit of oral administration of the activeingredient, but lacks a description for the vehicle by which suchadministration may be safely and routinely carried out. The presentinvention is directed to a solution to these and other problems.

SUMMARY OF THE INVENTION

The present invention is an oral hygiene product, and particularly atoothpaste product, that is laced into, or infused with, a sedative suchas the active therapeutic ingredients in cannabis. The act of brushingone's teeth using the present invention transfers the sedative into thebloodstream through contact with the gums to relax and sedate the user,leading to a more restful sleep. The present invention is healthier thanoral administration of narcotics or traditional powerful sleep aids thatcan be both addicting and hazardous to one's health.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

The following descriptions and discussion of the present invention isintended to disclose the inventor's best mode for preparing andpracticing the invention. A person of ordinary skill in the art willreadily recognize various modifications and substitutions, and theinvention is intended to include all such modifications andsubstitutions. Accordingly, the invention should not be construed aslimited to any particular embodiment or example disclosed herein, butrather should include all products and methods covered by the appendedclaims hereto.

A first embodiment of the present invention is a toothpaste product akinto those used by most people to brush their teeth. In the firstpreferred embodiment, a toothpaste mixture incorporating the inventionis manufactured by producing a pre-wetted binder with a humectant, andthen dispersing the mixture into a liquid phase of the formulation. Themixture is blended in a chemical mixer of the type known in the art toform a uniform paste. Alternatively, the binder may be premixed withsolid abrasives and then introduced into a mixing liquid phase of theformulation.

Cannabinoids used in this embodiment may be in liquid form, such as thatderived as a natural constituent of hemp oil or cannabis oil. In onepresenting preferred embodiment, toothpaste is manufactured with one ormore cannabinoids incorporated to provide both sedative features andanti-bacterial effects. In this embodiment, the one or more cannabinoidsare naturally derived or artificially derived.

When an oily form of cannabinoids is used, the viscosity of the oil ispreferably selected so as to be relatively high, usually in a paste-likematrix. The cannabinoid-containing oil is combined with a binder and ahumectant before introduction into the liquid phase. Alternatively, thecannabinoid oil is premixed with the binder and a solid abrasive beforeintroduction into the liquid phase for mixing. Solid and isolatedcannabinoids may also be used. Solid cannabinoids may be combined withthe binder and a humectant before introduction into the liquid phase.Solid cannabinoids may also be mixed with the binder and a solidabrasive prior to introduction into the liquid phase.

Abrasive agents used in toothpaste manufacturing include hydratedalumina, silica, water-insoluble sodium metaphosphate, tricalciumphosphate, calcium phosphate dihydrate, anhydrous dicalcium phosphate,calcium pyrophosphate, calcium carbonate, sodium bicarbonate, oraluminum silicate. Commercially available abrasive agents such asZeodent 113, Zeodent 115, or Zeodent 116 (silica abrasive agents) fallwithin the scope of the present invention, as does a combination ofthese abrasive agents. A thickener, such as Zeodent 163, may be usedtogether with other cleansing silica materials to thicken the toothpasteto a desirable viscosity.

Binders used in toothpaste manufacturing may be chosen from plant gumsuch as guar gum or xanthan gum, sodium alginate, karaya gum, bentonite,carrageenan, blanose cellulose gum, methylcellulose, and PEG-1500.Humectants may retain water in the toothpaste matrix and keep toothpastemade according to the instructions from excessively drying out.Sorbitol, glycerin, and propylene glycol may be used as humectants,where Glycerin and sorbitol may also yield a desirable sweet taste tothe toothpaste.

In the toothpaste, the one or more cannabinoids may be present at 0.1%to 0.5% by weight, and in some embodiments more specifically at 0.2% to0.4% by weight. For naturally derived cannabinoids, wherein the hemp oilor cannabis oil has multiple cannabinoids, at least one cannabinoid maybe present to comprise between 0.1% and 0.5% by weight of thetoothpaste. For artificially derived cannabinoids, adding one isolatedpurified cannabinoid, preferably chosen from the group comprising ofcannabidiol (“CBD”), cannabigerol (“CBG”), tetrahydrocannabinol (“THC”),cannabichromene (“CBC”), and cannabinol (“CBN”) is preferred. The amountof the artificial cannabinoid may be at 0.1% to 0.5% by weight of thetoothpaste.

Other components of the toothpaste may be used in sufficient amounts,including water, other preservatives, sweeteners, and flavoring oils toprepare and provide a consistent and pleasantly offering paste for useas a commercial toothpaste. Flavoring oils as used this embodiment maybe wintergreen, peppermint, spearmint, cinnamon, orange, watermelon,citrus, peach, apricot, anise, vanilla, clove, green tea, caraway,eucalyptus, sage, thyme, bourbon, rye, or other suitable flavors.Multiple flavors in combination may also be added. Coloring agents togive the toothpaste a desirable color may be added. Popular colors arewhite, blue, red, orange, and green. Coloring agents may be present inthe toothpaste at 1% to 3% by weight.

Preservatives suitable for food products and oral application may beadded into the toothpaste. Suitable preservatives include citric acid,trisodium citrate, alcohols, benzoates, and dechlorinated phenols.Citric acid and citrates are preferred preservatives for use with thefoundation of the invention for use within the formulation of theinvention.

Abrasive agents, humectants, binders, and cannabinoids may be combinedand mixed in a container, forming the first phase of the method ofproduces the toothpaste of the invention. The liquid phase, or thesecond phase, including water, fluoride compounds, preservatives,coloring agents, sweeteners, and flavoring oils, may be combined andmixed. Then, the first phase may be mixed into the second phase andstirred well with a mechanical impeller. Temperature control keeps themixture from drying out. Components of the tooth powder according tothis embodiment are preferably mixed by a solid mixer for evendistribution.

The toothpaste according to these embodiments may be safely used byplacing a sufficient quantity on a toothbrush. A user then appliesagitating force to his or her teeth using the toothbrush with thetoothpaste or tooth powder. The user then can rinse his or her mouthwith drinking water after brushing as is typical for such use.

Various oral infectious diseases may also be treated with cannabinoidoral care solutions due to their antibacterial, pain relieving, wounddressing, and anti-inflammation properties. Conditions treated by thesecannabinoid oral care compositions may include peri-implantitis,periodontitis, oral mucositis (especially oral mucositis caused bychemotherapy in cancer treatment), and dental pain. Cannabinoiddentifrice, including cannabinoid toothpaste, may be used in teethbrushing at a therapeutically effective amount to treatperi-implantitis, periodontitis, oral mucositis, and dental pain.

Example 1

This formulation makes approximately 405 grams of toothpaste.

Percent Ingredients/ Components Potential Supplier (%) Weight(g)Sorbo ®, Sorbitol Ingredion / PCC 27.6448 112.00 Solution USP/FCC(#260151) Emery ™ 917 Glycerine Emery 26.5587 107.60 Oleochemicals / PCCWater, filtered municipal 15.7970 64.00 Tixosil 43, amorphous Solvay /PCC 8.6390 35.00 precipitated silica Tixosil 73, amorphous Solvay / PCC5.1834 21.00 precipitated silica Sodium Lauryl Sulfate Bulk Apothecary4.9366 20.00 Xylitol Atlantic Chemical/PCC 3.0113 12.20 SOLEC F, DeoiledSoy SPI Group 2.2215 9.00 Lechithin Peppermint Oil, Arvensis Treatt, USA1.1107 4.50 (SA1120095/5) NATRACOL Titanium Roha, USA/PCC 0.9873 4.00Dioxide Dispersible 60% Xanthan Gum, Food Jungbunzlauer/PCC 0.8886 3.60Grade, FN Natural Flavor 0.5% OGAWA 0.7405 3.00 NAF A Sea Salt, FineCargill/PCC 0.4937 2.00 Delta- 9 THC JOYUS 0.4937 2.00 Benzyl AlcoholFuture Chemical 0.3949 1.60 CBD JOYUS 0.2468 1.00 Guar Gum PLTHealth/PCC 0.1975 0.80 Stevia - 98% Prescribed For Life 0.1975 0.80REbaudioside A SE CBN JOYUS 0.1234 0.50 CBG JOYUS 0.1234 0.50 LinaloolTRUE TERPENES 0.0025 0.01 Myrcene TRUE TERPENES 0.0025 0.01 NerolidolTRUE TERPENES 0.0025 0.01 Terpinolene TRUE TERPENES 0.0025 0.01 Totals:100.0000 405.14 Finished Product Specification: (Tested outside atArnesco Laboratories Delta-9 THC = Delta-9 CBD = Delta-9 CBN = Delta-9CBG = Linalool (Terpene) = Myrcene (Terpene) = Nerolidol (Terpene) =Terpinolene (Terpene) =

Bench Top Procedures:

1) Weigh the silicas and other dry ingredients and premix into quartmason jars.

2) In a Hobart mixer on a scale, add 1 jar of the dry ingredients andweigh the essential oils on top of that mixture.

3) In a 4 oz. mason jar, weigh glycerin and cannabis, mix together, thenheat to 180° F. in a water bath for 30 minutes, agitating frequentlyuntil homogeneously mixed.

4) Weigh the sodium lauryl sulfate and add to the dry ingredients in themixer bowl.

5) Weigh the sorbitol and add to the dry ingredients.

6) Weigh the Benzyl Alcohol and add to the dry ingredients.

7) Add the cannabis glycerin mixture to the dry ingredients.

8) Weigh the water, and rinse out container that cannabis was in whileagitating and add to dry ingredients, add the terpenes, begin to mix onlow speed until dry ingredients hydrate.

9) Finally, mix on high speed for approximately 1 minute to hydrate thegums to stabilize the system so syneresis does not occur through itsshelf life.

Examples of changes, substitutions, and alterations are ascertainable byone skilled in the art and could be made without departing from thescope of the information disclosed herein. All references cited areincorporated by reference herein in their entireties and made part ofthis application.

I claim:
 1. A method for manufacturing a cannabis laced toothpaste,comprising: 1) introducing silicas into a container; 2) forming amixture by adding an least one essential oil to the silicas; 3)modifying the mixture by adding sodium lauryl sulfate; 4) addingsorbitol to the mixture; 5) adding Benzyl Alcohol to the mixture; 6)separately heating a combination of glycerin and cannabis until ahomogeneous product is formed; 7) adding the glycerin and cannabisproduct to the mixture to form a composition; 8) adding water to thecomposition; 9) adding terpenes to the composition; 10) mixing thecomposition until the composition hydrates.
 2. A toothpaste made by themethod of claim 1.